V13M (p.Val13Met) variant of CD4 (T-cell surface glycoprotein CD4)
V13M (p.Val13Met) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
V13M (p.Val13Met) variant details
- p.Val13Met
- gnomAD 12-6800175-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.06
- MetaLR 0.10
- MetaSVM -1.03
- CADD 13.80
- PolyPhen-2 0.08
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available