T42A (p.Thr42Ala) variant of CD4 (T-cell surface glycoprotein CD4)
T42A (p.Thr42Ala) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
T42A (p.Thr42Ala) variant details
- p.Thr42Ala
- TOPMed rs1555115053
- gnomAD rs1555115053
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.12
- MetaLR 0.14
- MetaSVM -1.01
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available