T40I (p.Thr40Ile) variant of CD4 (T-cell surface glycoprotein CD4)
T40I (p.Thr40Ile) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
T40I (p.Thr40Ile) variant details
- p.Thr40Ile
- gnomAD 12-6800376-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.22
- MetaLR 0.22
- MetaSVM -0.76
- CADD 13.50
- PolyPhen-2 0.17
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available