T36R (p.Thr36Arg) variant of CD4 (T-cell surface glycoprotein CD4)
T36R (p.Thr36Arg) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
T36R (p.Thr36Arg) variant details
- p.Thr36Arg
- gnomAD 12-6800364-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.22
- MetaLR 0.17
- MetaSVM -0.81
- CADD 0.02
- PolyPhen-2 0.43
- SIFT 0.51
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available