T36I (p.Thr36Ile) variant of CD4 (T-cell surface glycoprotein CD4)
T36I (p.Thr36Ile) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
T36I (p.Thr36Ile) variant details
- p.Thr36Ile
- gnomAD 12-6800364-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.15
- MetaLR 0.16
- MetaSVM -0.97
- CADD 0.02
- PolyPhen-2 0.01
- SIFT 0.43
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available