T23S (p.Thr23Ser) variant of CD4 (T-cell surface glycoprotein CD4)
T23S (p.Thr23Ser) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T23S (p.Thr23Ser) variant details
- p.Thr23Ser
- TOPMed rs1237234163
- gnomAD rs1237234163
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.09
- MetaLR 0.12
- MetaSVM -1.02
- CADD 15.30
- SIFT 0.03
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available