S82L (p.Ser82Leu) variant of CD4 (T-cell surface glycoprotein CD4)
S82L (p.Ser82Leu) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
S82L (p.Ser82Leu) variant details
- p.Ser82Leu
- gnomAD 12-6814172-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.20
- MetaLR 0.41
- MetaSVM -0.73
- CADD 22.50
- PolyPhen-2 0.97
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available