S74P (p.Ser74Pro) variant of CD4 (T-cell surface glycoprotein CD4)
S74P (p.Ser74Pro) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
S74P (p.Ser74Pro) variant details
- p.Ser74Pro
- gnomAD 12-6814147-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.09
- MetaLR 0.33
- MetaSVM -0.69
- CADD 13.40
- PolyPhen-2 0.97
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available