S56T (p.Ser56Thr) variant of CD4 (T-cell surface glycoprotein CD4)
S56T (p.Ser56Thr) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
S56T (p.Ser56Thr) variant details
- p.Ser56Thr
- ExAC rs782791509
- gnomAD rs782791509
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.15
- MetaLR 0.23
- MetaSVM -0.89
- CADD 0.09
- PolyPhen-2 0.05
- SIFT 0.33
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available