R8W (p.Arg8Trp) variant of CD4 (T-cell surface glycoprotein CD4)
R8W (p.Arg8Trp) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R8W (p.Arg8Trp) variant details
- p.Arg8Trp
- Ensembl rs1942496138
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.21
- MetaLR 0.14
- MetaSVM -0.96
- CADD 9.38
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available