R8S (p.Arg8Ser) variant of CD4 (T-cell surface glycoprotein CD4)
R8S (p.Arg8Ser) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
R8S (p.Arg8Ser) variant details
- p.Arg8Ser
- gnomAD 12-6800162-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.12
- MetaLR 0.17
- MetaSVM -1.01
- CADD 9.60
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available
- Literature evidence available