R79C (p.Arg79Cys) variant of CD4 (T-cell surface glycoprotein CD4)
R79C (p.Arg79Cys) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R79C (p.Arg79Cys) variant details
- p.Arg79Cys
- cosmic curated COSV10500
- ExAC rs200264344
- TOPMed rs200264344
- gnomAD rs200264344
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.30
- MetaLR 0.51
- MetaSVM -0.45
- CADD 23.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available