R3Q (p.Arg3Gln) variant of CD4 (T-cell surface glycoprotein CD4)
R3Q (p.Arg3Gln) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
R3Q (p.Arg3Gln) variant details
- p.Arg3Gln
- ExAC rs782252955
- TOPMed rs782252955
- gnomAD rs782252955
- Missense
- Variant Prioritization Score for Impact Estimate 0.0873
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.07
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.84
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available