Q50H (p.Gln50His) variant of CD4 (T-cell surface glycoprotein CD4)
Q50H (p.Gln50His) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
Q50H (p.Gln50His) variant details
- p.Gln50His
- gnomAD 12-6800407-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.18
- MetaLR 0.16
- MetaSVM -1.01
- CADD 0.95
- PolyPhen-2 0.36
- SIFT 0.54
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available