Q45R (p.Gln45Arg) variant of CD4 (T-cell surface glycoprotein CD4)
Q45R (p.Gln45Arg) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
Q45R (p.Gln45Arg) variant details
- p.Gln45Arg
- ExAC rs374341894
- gnomAD rs374341894
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.11
- MetaLR 0.21
- MetaSVM -1.01
- CADD 0.02
- PolyPhen-2 0.16
- SIFT 0.07
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available