Q45E (p.Gln45Glu) variant of CD4 (T-cell surface glycoprotein CD4)
Q45E (p.Gln45Glu) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
Q45E (p.Gln45Glu) variant details
- p.Gln45Glu
- gnomAD 12-6800390-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.10
- MetaLR 0.17
- MetaSVM -1.08
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available
- Literature evidence available