Q15E (p.Gln15Glu) variant of CD4 (T-cell surface glycoprotein CD4)
Q15E (p.Gln15Glu) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
Q15E (p.Gln15Glu) variant details
- p.Gln15Glu
- ExAC rs781864508
- gnomAD rs781864508
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.09
- MetaLR 0.13
- MetaSVM -0.98
- CADD 20.80
- PolyPhen-2 0.45
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available