P20T (p.Pro20Thr) variant of CD4 (T-cell surface glycoprotein CD4)
P20T (p.Pro20Thr) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P20T (p.Pro20Thr) variant details
- p.Pro20Thr
- TOPMed rs1555115033
- gnomAD rs1555115033
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.05
- MetaLR 0.05
- MetaSVM -1.04
- CADD 7.68
- PolyPhen-2 0.20
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available