P20A (p.Pro20Ala) variant of CD4 (T-cell surface glycoprotein CD4)
P20A (p.Pro20Ala) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
P20A (p.Pro20Ala) variant details
- p.Pro20Ala
- gnomAD 12-6800315-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.05
- MetaLR 0.05
- MetaSVM -1.02
- CADD 1.22
- PolyPhen-2 0.03
- SIFT 0.14
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available
- Literature evidence available