N77S (p.Asn77Ser) variant of CD4 (T-cell surface glycoprotein CD4)
N77S (p.Asn77Ser) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
N77S (p.Asn77Ser) variant details
- p.Asn77Ser
- gnomAD 12-6814157-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0741
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.02
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.81
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available
- Literature evidence available