N2I (p.Asn2Ile) variant of CD4 (T-cell surface glycoprotein CD4)
N2I (p.Asn2Ile) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
N2I (p.Asn2Ile) variant details
- p.Asn2Ile
- gnomAD 12-6800143-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.04
- MetaLR 0.14
- MetaSVM -0.91
- CADD 6.57
- PolyPhen-2 0.17
- SIFT 0.02
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available
- Literature evidence available