L39P (p.Leu39Pro) variant of CD4 (T-cell surface glycoprotein CD4)
L39P (p.Leu39Pro) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
L39P (p.Leu39Pro) variant details
- p.Leu39Pro
- ExAC rs782647911
- gnomAD rs782647911
- Missense
- Variant Prioritization Score for Impact Estimate 0.688
- REVEL 0.73
- MetaLR 0.69
- MetaSVM 0.49
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available