L19H (p.Leu19His) variant of CD4 (T-cell surface glycoprotein CD4)
L19H (p.Leu19His) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
L19H (p.Leu19His) variant details
- p.Leu19His
- gnomAD 12-6800313-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.15
- MetaLR 0.15
- MetaSVM -0.98
- CADD 20.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available
- Literature evidence available