L19F (p.Leu19Phe) variant of CD4 (T-cell surface glycoprotein CD4)
L19F (p.Leu19Phe) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L19F (p.Leu19Phe) variant details
- p.Leu19Phe
- gnomAD 12-6800312-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.14
- MetaLR 0.14
- MetaSVM -1.04
- CADD 18.20
- PolyPhen-2 0.98
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available