L18P (p.Leu18Pro) variant of CD4 (T-cell surface glycoprotein CD4)
L18P (p.Leu18Pro) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
L18P (p.Leu18Pro) variant details
- p.Leu18Pro
- Ensembl rs1591547179
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.17
- MetaLR 0.13
- MetaSVM -1.02
- CADD 19.60
- PolyPhen-2 0.85
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available