L14M (p.Leu14Met) variant of CD4 (T-cell surface glycoprotein CD4)
L14M (p.Leu14Met) in CD4 (T-cell surface glycoprotein CD4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes structural context.
L14M (p.Leu14Met) variant details
- p.Leu14Met
- rs1555114978
- NCI-TCGA Cosmic COSV9916
- cosmic curated COSV99163
- gnomAD rs1555114978
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.487
- AlphaMissense 0.19
- MetaLR 0.35
- MetaSVM -0.65
- PolyPhen-2 1.00
- SIFT 0.00
- EVE 0.73
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available