L10F (p.Leu10Phe) variant of CD4 (T-cell surface glycoprotein CD4)
L10F (p.Leu10Phe) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L10F (p.Leu10Phe) variant details
- p.Leu10Phe
- ESP rs151325091
- ExAC rs151325091
- TOPMed rs151325091
- gnomAD rs151325091
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.22
- MetaLR 0.32
- MetaSVM -0.72
- CADD 22.90
- PolyPhen-2 0.89
- SIFT 0.53
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available