K54R (p.Lys54Arg) variant of CD4 (T-cell surface glycoprotein CD4)
K54R (p.Lys54Arg) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
K54R (p.Lys54Arg) variant details
- p.Lys54Arg
- ExAC rs782107070
- TOPMed rs782107070
- gnomAD rs782107070
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.24
- MetaLR 0.33
- MetaSVM -0.62
- CADD 16.20
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available