K47R (p.Lys47Arg) variant of CD4 (T-cell surface glycoprotein CD4)
K47R (p.Lys47Arg) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
K47R (p.Lys47Arg) variant details
- p.Lys47Arg
- gnomAD 12-6800397-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0923
- REVEL 0.06
- MetaLR 0.15
- MetaSVM -0.98
- CADD 0.21
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available