K32I (p.Lys32Ile) variant of CD4 (T-cell surface glycoprotein CD4)
K32I (p.Lys32Ile) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
K32I (p.Lys32Ile) variant details
- p.Lys32Ile
- ExAC rs782235609
- TOPMed rs782235609
- gnomAD rs782235609
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.24
- MetaLR 0.39
- MetaSVM -0.46
- CADD 19.80
- PolyPhen-2 0.49
- SIFT 0.00
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available