I61T (p.Ile61Thr) variant of CD4 (T-cell surface glycoprotein CD4)
I61T (p.Ile61Thr) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
I61T (p.Ile61Thr) variant details
- p.Ile61Thr
- gnomAD rs1555115080
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.33
- MetaLR 0.17
- MetaSVM -0.91
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available