I59Y (p.Ile59Tyr) variant of CD4 (T-cell surface glycoprotein CD4)
I59Y (p.Ile59Tyr) in CD4 (T-cell surface glycoprotein CD4) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
I59Y (p.Ile59Tyr) variant details
- p.Ile59Tyr
- gnomAD 12-6800431-G-GT
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.18
- CADD 14.00
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available