I59V (p.Ile59Val) variant of CD4 (T-cell surface glycoprotein CD4)
I59V (p.Ile59Val) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
I59V (p.Ile59Val) variant details
- p.Ile59Val
- gnomAD 12-6800432-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0943
- REVEL 0.02
- MetaLR 0.03
- MetaSVM -1.03
- CADD 12.70
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available
- Literature evidence available