I59M (p.Ile59Met) variant of CD4 (T-cell surface glycoprotein CD4)
I59M (p.Ile59Met) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
I59M (p.Ile59Met) variant details
- p.Ile59Met
- gnomAD 12-6800434-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0703
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.01
- CADD 0.92
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available