I59L (p.Ile59Leu) variant of CD4 (T-cell surface glycoprotein CD4)
I59L (p.Ile59Leu) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
I59L (p.Ile59Leu) variant details
- p.Ile59Leu
- gnomAD 12-6800432-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0663
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.04
- CADD 1.14
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available