I59K (p.Ile59Lys) variant of CD4 (T-cell surface glycoprotein CD4)
I59K (p.Ile59Lys) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I59K (p.Ile59Lys) variant details
- p.Ile59Lys
- TOPMed rs199890832
- gnomAD rs199890832
- Missense
- Variant Prioritization Score for Impact Estimate 0.0778
- REVEL 0.05
- MetaLR 0.03
- MetaSVM -0.94
- CADD 0.00
- PolyPhen-2 0.08
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available