I49T (p.Ile49Thr) variant of CD4 (T-cell surface glycoprotein CD4)
I49T (p.Ile49Thr) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
I49T (p.Ile49Thr) variant details
- p.Ile49Thr
- TOPMed rs1942509499
- gnomAD rs1942509499
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.30
- MetaLR 0.09
- MetaSVM -0.92
- CADD 0.03
- SIFT 0.41
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available