I49M (p.Ile49Met) variant of CD4 (T-cell surface glycoprotein CD4)
I49M (p.Ile49Met) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
I49M (p.Ile49Met) variant details
- p.Ile49Met
- TOPMed rs903424784
- gnomAD rs903424784
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.19
- MetaLR 0.09
- MetaSVM -1.01
- CADD 0.05
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available