H9L (p.His9Leu) variant of CD4 (T-cell surface glycoprotein CD4)
H9L (p.His9Leu) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
H9L (p.His9Leu) variant details
- p.His9Leu
- gnomAD rs1555114972
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.17
- MetaLR 0.14
- MetaSVM -0.97
- CADD 5.04
- PolyPhen-2 0.17
- SIFT 0.11
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available