G66S (p.Gly66Ser) variant of CD4 (T-cell surface glycoprotein CD4)
G66S (p.Gly66Ser) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
G66S (p.Gly66Ser) variant details
- p.Gly66Ser
- gnomAD 12-6800453-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.17
- MetaLR 0.15
- MetaSVM -1.00
- CADD 0.00
- PolyPhen-2 0.03
- SIFT 0.46
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available
- Literature evidence available