G63R (p.Gly63Arg) variant of CD4 (T-cell surface glycoprotein CD4)
G63R (p.Gly63Arg) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G63R (p.Gly63Arg) variant details
- p.Gly63Arg
- TOPMed rs1942510525
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.27
- MetaLR 0.32
- MetaSVM -0.65
- CADD 17.00
- PolyPhen-2 0.89
- SIFT 0.39
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available