G4E (p.Gly4Glu) variant of CD4 (T-cell surface glycoprotein CD4)
G4E (p.Gly4Glu) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G4E (p.Gly4Glu) variant details
- p.Gly4Glu
- cosmic curated COSV10608
- 1000Genomes rs142478992
- ESP rs142478992
- ExAC rs142478992
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.17
- MetaLR 0.15
- MetaSVM -1.04
- CADD 8.69
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available