G25E (p.Gly25Glu) variant of CD4 (T-cell surface glycoprotein CD4)
G25E (p.Gly25Glu) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
G25E (p.Gly25Glu) variant details
- p.Gly25Glu
- 1000Genomes rs202129605
- ExAC rs202129605
- TOPMed rs202129605
- gnomAD rs202129605
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- REVEL 0.28
- MetaLR 0.24
- MetaSVM -0.84
- CADD 14.50
- PolyPhen-2 0.81
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available