F7C (p.Phe7Cys) variant of CD4 (T-cell surface glycoprotein CD4)
F7C (p.Phe7Cys) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
F7C (p.Phe7Cys) variant details
- p.Phe7Cys
- TOPMed rs1164548089
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.16
- MetaLR 0.28
- MetaSVM -0.93
- CADD 21.40
- PolyPhen-2 0.67
- SIFT 0.09
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available