F51L (p.Phe51Leu) variant of CD4 (T-cell surface glycoprotein CD4)
F51L (p.Phe51Leu) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
F51L (p.Phe51Leu) variant details
- p.Phe51Leu
- gnomAD 12-6800408-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.30
- MetaLR 0.30
- MetaSVM -0.56
- CADD 23.20
- PolyPhen-2 0.84
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available