D81V (p.Asp81Val) variant of CD4 (T-cell surface glycoprotein CD4)
D81V (p.Asp81Val) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
D81V (p.Asp81Val) variant details
- p.Asp81Val
- TOPMed rs200573785
- gnomAD rs200573785
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.29
- MetaLR 0.45
- MetaSVM -0.44
- CADD 23.70
- PolyPhen-2 0.97
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available