D81N (p.Asp81Asn) variant of CD4 (T-cell surface glycoprotein CD4)
D81N (p.Asp81Asn) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
D81N (p.Asp81Asn) variant details
- p.Asp81Asn
- gnomAD 12-6814168-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.25
- MetaLR 0.36
- MetaSVM -0.56
- CADD 16.80
- PolyPhen-2 0.16
- SIFT 0.09
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available