D81H (p.Asp81His) variant of CD4 (T-cell surface glycoprotein CD4)
D81H (p.Asp81His) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
D81H (p.Asp81His) variant details
- p.Asp81His
- gnomAD 12-6814168-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.21
- MetaLR 0.51
- MetaSVM -0.38
- CADD 21.50
- PolyPhen-2 0.98
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available