D35N (p.Asp35Asn) variant of CD4 (T-cell surface glycoprotein CD4)
D35N (p.Asp35Asn) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
D35N (p.Asp35Asn) variant details
- p.Asp35Asn
- TOPMed rs1328368781
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.05
- MetaLR 0.22
- MetaSVM -0.92
- CADD 7.43
- PolyPhen-2 0.06
- SIFT 0.24
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available