D35G (p.Asp35Gly) variant of CD4 (T-cell surface glycoprotein CD4)
D35G (p.Asp35Gly) in CD4 (T-cell surface glycoprotein CD4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
D35G (p.Asp35Gly) variant details
- p.Asp35Gly
- gnomAD 12-6800361-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.13
- MetaLR 0.10
- MetaSVM -1.00
- CADD 0.23
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available
- Literature evidence available